Synopsis: After losing his wife (Kasia Smutniak) seven years earlier, the eccentric Dr. John Dolittle (Downey), famed doctor and veterinarian of Queen Victorias England, hermits himself away behind the high walls of Dolittle Manor with only his menagerie of exotic animals for company.
But when the young queen (Jessie Buckley) falls gravely ill, a reluctant Dolittle is f-rced to set sail on an epic adventure to a mythical island in search of a cure, regaining his wit and courage as he crosses old adversaries and discovers wondrous creatures.
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