Synopsis: Half-white, half-Comanche twin brothers Johnny Moon and Notah have long been estranged, but things are even worse now that Notah is a bloodthirsty outlaw, and people mistake Johnny for him. Addicted to peyote, Notah believes himself destined to lead the Comanche to victory over the whites. Despite Johnny's pleas, his brother plans to destroy Rio Hondo, which is protected by Sheriff Logan. Will Johnny side with the town or his brother?